請教台灣核准的農業用礦物油相關藥劑的標準是否有高於WHO底下的IARC的一級致癌物的未處理礦物油的範圍
http://monographs.iarc.fr/ENG/Classification/index.php
Group 1 Carcinogenic to humans 111 agents
Mineral oils, untreated or mildly treated 1 33, Sup 7, 100F 2012
http://monographs.iarc.fr/ENG/Monographs/vol100F/mono100F-19.pdf
There are several assays that can be used to determine if a mineral oil is highly or severely refined (Mackerer et al., 2003). Two useful short-term assays that are widely used by mineraloil manufacturers are the modified Ames test (ASTM, 1996) and the IP346 assay (Institute for Petroleum, 1985, 1993; CONCAWE, 1994). The
modified Ames test measures the amount of extractable mutagenic activity in a mineral-oil sample; mineral oils with a mutagenicity index ≤ 1.0 in this assay are considered highly or severely refined. The IP346 assay measures the amount
of material extractable in dimethyl sulfoxide (DMSO): mineral oils with a DMSO-extractable content < 3% in the IP346 assay are considered highly or severely refined. Naphthenic mineral oils tend to have higher non-mutagenic DMSO
extractables and some naphthenic oils can give a false-positive result in the IP346 assay. The modified Ames test can give conclusive results if the outcome of the IP346 assay is high.
專家回覆
1 則
![農業達人](/images/seticon/seticon1-4.jpg)
1.由台端提供之IARC針對未處理或輕度處理礦物油 (mineral oils, untreated or mildly treated) 的致癌性評估中,建議區別礦物油是否高度精製過以去除致癌不純物的所使用的方法中,modified Ames test屬於致變異性試驗,可用來檢測礦物油中是否含有部分致癌的不純物。
2.目前農藥在新有效成分或核准登記屆滿八年農藥原體登記時均需繳交致變異性試驗,其目的亦為檢測原體製程是否產生有害的不純物。由於農藥登記審核過程為層層把關,雖然在毒理試驗上並未針對礦物油是否高度精製以去除致癌不純物來要求,但在農藥登記上仍需繳交製程、有效成分、其他成分和規格檢驗供專家進行檢視和分析。
藥毒所
本篇討論
2 則
![甜八寶](/files/member/57252/tuntuntun_20120918023306_s.jpg)
http://www.ag168.com/news/news/news20194.htm
![蠻頭](/files/member/59881/winnie_20140729015302_s.jpg)
我國目前要求農用礦物油未磺化值需在92%以上。油劑對表生病害,例如:白粉病、黑星病、銹病、灰黴病及煤煙病等防治效果良好,此外,對移動性差的小型昆蟲,例如:薊馬、介殼蟲、蚜蟲、紅蜘蛛等防治效果也非常顯著。其優點為價格便宜,耐雨水沖刷,效果持久,有機農法亦可使用,另外也可作為許多藥劑的協力劑;缺點則是品質不良的產品或使用不當時易引起藥害。
https://www.google.com.tw/url?sa=t&rct=j&q=&esrc=s&source=web&cd=7&ved=0CF0QFjAG&url=http%3A%2F%2Fkmsafe.kinmen.gov.tw%2Fupload%2Fcht%2Fattachment%2F5180eec00db40a8685c2f7f39f76a41a.pdf&ei=DKHwUYjtC8PKkwWrqIDwCA&usg=AFQjCNET2ZR5nt7JiB4Anl2aTLwJP36SIQ&bvm=bv.49784469,d.dGI&cad=rja